Research Paper Volume 8, Issue 10 pp 2488—2508

Dissociation between iron accumulation and ferritin upregulation in the aged substantia nigra: attenuation by dietary restriction

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Figure 4. Nonlinear regression and Spearman's rank-order correlation of (A) R1 (B) R2 and (C) R2* with iron in the basal ganglia. A significant positive correlation of iron was found for all MR relaxation rates, but nonlinear regression demonstrated R2* to have the greatest predictive value for iron. Significance level of correlation at ***, P < 0.001.