Review Volume 8, Issue 10 pp 2290—2307
The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis
Figure 1. Role of Sirt1 in vascular aging and atherosclerosis. Sirt1 may increase nitric oxide (NO) production, decrease inflammation, reduce oxidative stress, induce autophagy, and prevent senescence, resulting in the suppression of vascular aging and atherosclerosis.