Research Paper Volume 8, Issue 10 pp 2463—2487
Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury
Figure 8. PRG3 impedes Thrombin-induced axon collapse. (A) Representative time laps microscopy image series of GFP and PRG3 expressing neurons treated with 25 µM Thrombin (TRP). Transfection efficacy is shown in first image bottom right corner. Scale bar represents 50 µm. (B) Quantification of neurite length of neurons expressing GFP (control) or PRG3. Three independent experiments were carried out and differences were considered statistically significant with * p<0.05, ** p<0.01, *** p<0.001 (two-tailed t-test). Values are given as mean ± SEM.