Research Paper Volume 8, Issue 10 pp 2370—2391

A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated

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Figure 8. Premature mortality was not correlated with performance in healthspan measures. (A) Grip strength, rotarod, dark activity and sleep fragmentation were not significantly associated with premature mortality in females, p > 0.99, p = 0.18, p > 0.99, p > 0.99, respectively. (B) Grip strength, rotarod, dark activity and sleep fragmentation were not significantly associated with premature mortality in males, p = 0.240, p > 0.99, p > 0.99, p > 0.99, respectively. All tests subjected to Bonferroni corrections for multiple comparisons. Animals suffering premature mortality shown in blue, survivors in black.