Research Paper Volume 8, Issue 11 pp 2734—2746

Figure 2. The serum levels of IL23A in IDD and normal groups were detected by ELISA. (A) The expression levels of IL23A in the MS patients were higher than that in the control group (two asterisk); and when both the IL-23A and IL-23R genes were altered, the serum levels of IL23A were higher than those in the groups in which neither the IL-23A nor the IL-23R gene was altered or only one of them was altered. (B) The expression levels of IL23A in the RIS patients were higher than those in the control group (two asterisks); however there was no difference between the three groups that had the IL-23A and IL-23R genes both altered, only one altered or neither altered. “WW” means neither the IL-23A nor the IL-23R gene was altered; “MM” means the IL-23A and IL-23R genes were both altered; “Homozygous variant” means the homozygous variant G/G of the rs1884444 variant in the IL-23R gene.