Research Paper Volume 8, Issue 7 pp 1513—1539

Dietary and microbiome factors determine longevity in Caenorhabditis elegans

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Figure 6. Genetic interventions that affect the life span of worms fed E. coli do not always lead to similar effects in worms fed B. subtilis. (A) Median life span ± S.E.M. of 14 mutant strains as well as WT worms when worms are fed E. coli or B. subtilis. Perpendicular dotted lines are reference lines representing the median life span of WT worms on each diet. The diagonal dotted line represents a perfect proportionality between median life span for mutant worms upon feeding B. subtilis relative to feeding E. coli, based on the WT median life span results. See also Table S6. (B) Bars represent the percentage of life span increase or decrease for mutant worms fed E. coli or B. subtilis relative to WT worms fed the same type of diet. Indicated is the mutant and allele used in each life span experiment.