Research Paper Volume 8, Issue 7 pp 1442—1456
miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cells
Figure 2. SMC1A is a target of miR-638. (A) The scheme illustrates the vector structure that was used for target validation and the predicted miR-638 binding sites in the 3′UTR of SMC1A mRNA. SMC1A-MUT has a seven-base mutation at the 3′UTR. (B) Luciferase activities were measured and normalized by Renilla luciferase expression. Data are presented as relative luciferase activity. *: p<0.05, compared to control with the Student's t test. Error bars, S.D.