Research Paper Volume 8, Issue 7 pp 1416—1431
Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans
Figure 3. Change in plasma concentrations of inflammation markers following 2 years of calorie restriction in humans. Panel (A) baseline values of C-reactive protein (hs-CRP) for ad libitum (AL) and calorie-restricted (CR) groups were 1.1 and 1.5 μg/mL, respectively. Panel (B) baseline values of tumor necrosis factor-alpha (TNF-α) for AL and CR groups were 3.1 and 3.5 pg/ml, respectively. Panel (C) baseline values of intercellular adhesion molecule-1 (ICAM-1) for AL and CR groups were 165.4 and 165.0 ng/ml, respectively. Panel (D) baseline values of leptin for AL and CR groups were 17.7 and 16.9 ng/ml, respectively. Data are mean (SE). The P value comparisons are for AL and CR groups at indicated time points.