Research Paper Volume 8, Issue 5 pp 1064—1078

SIRT6 protects against endothelial dysfunction and atherosclerosis in mice

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Figure 5. SIRT6 deficiency increases VCAM-1 expression in ApoE−/− mice. Aortic sinus from SIRT6+/+; ApoE−/− and SIRT6+/−; ApoE−/− mice were stained with VCAM-1 (red) antibody. DAPI was used to counterstain cell nuclei, bar=30 um, n=4-6/each genotype.