Research Paper Volume 8, Issue 5 pp 977—985
Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis
Figure 1. Levels of MAP1S are decreased and levels of fibronectin are elevated in renal tissues from patients suffering from renal fibrosis. (A) Representative images showing the H&E staining of renal tissues collected from patients suffering from renal fibrosis and healthy control. The area containing a glomerulus or distal and proximal convoluted tubules is amplified (200X) to show the detail structures. (B) Representative images showing the immuno-florescent staining of MAP1S (green), fibronectin (red) and nuclear DNA (blue) in the normal and renal fibrotic tissues. Scale Bar: 100 μm.