Figure 3. Results of Open field test in female mice aged 2 and 8 months (Wt and 5XFAD). Time spent in center zone., (A), Time spent in border maze (B), Locomotor activity (C) and Rears (D). Representative tracks for the OFT (E). Data represented as observed mean ± Standard Error of the Mean (SEM) (n = 10 for each group). *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001.