Aging
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Figure 6
Figure 6.CDK inhibitor accelerates senescence in HGPS fibroblasts(A) Population doublings calculated after serial passage of the cells starting at population doubling 9 and treated with vehicle or 60 nM flavopiridol for the indicated amount of days. (B) Immunoblots in cells as in (A) for the indicated proteins.
Figure 6 — Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase | Aging