Research Paper Volume 7, Issue 10 pp 816—838

Figure 8. Clinical correlations of UBA1 expression and the UBA1, PSMC5, IGF2R, VAT1, HMOX1, CNN2, TLN1, GNPDA1, G6PD and FASN signature in chemotherapy-treated lung, gastric and ovarian cancer patients. (A) Correlations of UBA1 expression with overall survival in lung and gastric cancer, and with progression-free survival in ovarian cancer. (B) Correlations of the catabolic stroma signature with overall survival in lung and gastric cancer, and with progression-free survival in ovarian cancer. All graphs are calculated using microarray data from 176 chemotherapy-treated lung cancers, 153 5-FU-based adjuvant therapy-treated gastric cancers, and 229 paclitaxel-treated ovarian cancers, determined using an online survival analysis tool. Kaplan-Meier correlations are plotted for high (above median, in red) and low (below median, in black) gene expression.