Research Paper Volume 7, Issue 10 pp 816—838
Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts
Figure 7. Clinical correlations of UBA1 expression and the UBA1, PSMC5, IGF2R, VAT1, HMOX1, CNN2, TLN1, GNPDA1, G6PD and FASN signature in chemotherapy-treated breast cancer patients. (A) Correlations of UBA1 expression with relapse-free survival, distant metastasis-free survival and overall survival in breast cancer. (B) Correlations of the catabolic stroma signature with relapse-free survival, distant metastasis-free survival and overall survival in breast cancer. All graphs are calculated using microarray data from 425, 122 and 69 chemotherapy-treated breast cancers, respectively, determined using an online survival analysis tool. Kaplan-Meier correlations are plotted for high (above median, in red) and low (below median, in black) gene expression.