Research Paper Volume 7, Issue 8 pp 553—567

Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2

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Figure 2. (A) Survival curves for TG38 AMPK/akk-2(gt33), fed with E. coli GC363 harboring the empty vector L4400 (empty vector control) versus E. coli GC363 harboring INDY/CeNAC2-specific siRNA and CB1370 daf-2(e1370) fed with empty vector control. (B) Survival curves for N2 (WT), fed with E.coli GC363 harboring the empty vector L4400 (empty vector control) versus E.coli GC363 harboring INDY/CeNAC2 siRNA with 2-Deoxy-D-Glucose (DOG+) in the media.