The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila
Figure 3.Mifepristone prevents the life span decrease caused by mating. Strains and crosses used to generate the 11 female genotypes are indicated (A-K; life span curves shown in Figure 2; statistical summary in Table 1). (A) The percent decrease in female life span caused by mating (X-axis) is compared to the percent increase in life span caused by mifepristone in mated females (Y-axis). (B) The median life span of virgin females (X-axis) is compared to the percent increase in life span caused by mifepristone in mated females (Y-axis).