Figure 1.Mifepristone life span increase depends on sex and genotypeSurvival curves are presented for male and female flies cultured as adults in the presence and absence of 160ug/ml mifepristone, for progeny of the indicated crosses (written in order male x female). (A) Control w[1118] strain crossed to y; Elav-GS. (B) Control w[1118] crossed to the backcrossed strain w[1118]; Elav-GS. (C) Control w[1118] strain crossed to Actin-GS-255B. (D) Control w[1118] strain crossed to y; Elav-GS. (E) Tet-on system strain p53B[6] crossed to w; rtTA(3)E2. (A, C) Flies were allowed to eclose for 48 hours prior to sorting. (B, E) Flies were allowed to eclose for 48 hours and then allowed to mate to siblings for an additional 48 hours prior to sorting. (D) Females were collected as virgins over 24 hours, then mated to w[1118] males for two days. Statistical summary in Table 1.
