← Back
Research Paper Volume 6, Issue 12 pp 1033—1048

Stochastic modeling indicates that aging and somatic evolution in the hematopoietic system are driven by non-cell-autonomous processes

class="figure-viewer-img"

Figure 3. HSC division rates and pool size change dramatically throughout life. (A) Dynamics of the pool size; the dynamics were inferred based on postnatal and adult HSC pool size estimates in [49, 72] (B) Average cell division frequencies; modeled based on estimates of HSC division rates at different ages in [20, 21, 49].