Research Paper Volume 6, Issue 10 pp 788—819

Figure 4. Eryptosis and its signalling molecules: the changes it effects on erythrocytes. Prominent triggers are hyperosmotic shock and oxidative stress. These triggers result in three morphologically visible changes to RBCs and these are phospholipid membrane scrambling (1); cell shrinkage (2) and membrane blebbing (3); when any of these changes are noted in RBCs, the phenomenon is collectively known as eryptosis.