Figure 3. Analysis of the superoxide detoxifying enzymes in atypical Werner syndrome and Werner syndrome fibroblasts. (A) Mean (±SD) mRNA levels of the SOD1 gene determined by qRT-PCR by triplicate. (B) Mean (±SD) mRNA levels of the SOD2 gene determined by qRT-PCR by triplicate. (C) CuZnSOD and MnSOD protein levels measured by Western blot in AWS, WS, and control fibroblasts.