Research Paper Volume 6, Issue 1 pp 35—47

Figure 3. Overexpression of macroH2A1 isoforms (macroH2A1.1 or macroH2A1.2) and glycogen synthesis (A) and glucose uptake (B) content in Hepa1-6 and HepG2 cells. A, B: cells were transiently transfected as described in the legends of Figure 2. Glycogen content (A) and glucose uptake (B) were assessed by stimulation with 10⁻⁷ mol/L insulin, using [3-3H]-glucose incorporation and 2-deoxy-D-[2,6-3H]-glucose uptake, respectively. Results are expressed as percentage of controls, means ± SEM of four independent experiments. *p<0.05.