Research Perspective Volume 5, Issue 10 pp 782—788

Aging on a different scale – chronological versus pathology-related aging

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Figure 3. Overlap analysis of functional responses in chronological and pathology-related aging. Summarized Metacore GeneGO pathways and GO responses are color coded. For chronological and each pathological parameter in liver the functional responses are plotted. Overlapping bars represent overlapping functional responses, e.g. the majority of mitochondrial/organelle-related responses are related to chronological aging, lipofuscin accumulation and karyomegaly. Immune responses are correlated to several age-related pathologies in liver.