Research Paper Volume 5, Issue 6 pp 474—484

Figure 2. Open field performance in 3.5 month old control and rapamycin-treated OXYS rats and Wistar rats. Treatment (0.1 or 0.5 mg/kg?day rapamycin) was started at 1.5 months. OXYS rats had reduced number of squares crossed (A), frequencies of rearing (B), and increased latency time to enter the centre (C), grooming frequency (D) compared to Wistar rats. In rapamycin-treated OXYS rats the number of squares crossed, frequencies of rearing increased, latency time to enter the centre and grooming frequency were decreased. Legend: ^#p < 0.05 as the difference between the rat strains and *p < 0.05 as compared of Rapamycin-treated to the control OXYS rats.