Research Paper Volume 5, Issue 3 pp 174—182

Figure 4. Effects of syringaresinol treatment on endothelial functions. (A) Protein levels of eNOS, PAI-1, and acetylation of p53 (Ac-p53) at lysine 373/382 in HUVECs at PDL40 treated every 48 hours starting from PDL14 with different doses of syringaresinol (SYR). (B) NOS activities measured in HUVEC cultured in different doses of syringaresinol. (C-D) Protein levels of SIRT1, eNOS and PAI-1 in HUVECs at PDL14 treated with siRNAs against SIRT1 (C) and FOXO3 (D). All the results are either representatives or means ± S.E of at least three independent experiments. Significance was assessed by t-test. *P < 0.05.