Research Paper Volume 5, Issue 3 pp 174—182

Figure 1. Activation of SIRT1 gene expression by syringaresinol. (A) SIRT1 protein levels were determined by Western blot in PDL 14, 24, and 40 of HUVECs. (B) mRNA levels of SIRT1 are measured in PLD 40 HUVECs cultured with various doses of syringaresinol (SYR) from the PDL14. (C) SIRT1 protein levels (western blot) at PDL40 in HUVECs treated every 48 hours starting from PDL14 with different doses of syringaresinol. (D) Chemical structure of (+)-syringaresinol purified from Panax ginseng berry pulp. All the results are either representatives or means ± S.E of at least three independent experiments. Significance was assessed by t-test. *P < 0.05, **P > 0.01.