Figure 1 — How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a

Research Paper|Volume 5, Issue 2|pp. 120–129

How to measure RNA expression in rare senescent cells expressing any specific protein such as p16^Ink4a

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Figure 1.Expression of p16 at the single cell level measured by immunostaining with a p16 antibody followed by immunohistochemical detection(A) Non-immortalized HDF (LF1) at early passage. (B) LF1 HDF passaged into senescence. (C) LF1 cells immortalized with telomerase (LF1/TERT) under conditions of exponential proliferation.