Figure 5. Blood pressure in WT, mIGF-1 Tg and mIGF-1 Tg; SIRT1 CKO mice. Noninvasive blood pressure values in conscious mice were measured using the tail-cuff method. (A) Diastolic blood pressure (DBP); (B) Systolic blood pressure (SBP). Results are means ± SE of 3-8 animals for each genotype (*p versus WT mice). NS= not significant.