Figure 8 — Store-Operated Ca2+ Entry (SOCE) Contributes to Normal Skeletal Muscle Contractility in young but not in aged skeletal muscle

Research Paper|Volume 3, Issue 6|pp. 621–634

Store-Operated Ca²⁺ Entry (SOCE) Contributes to Normal Skeletal Muscle Contractility in young but not in aged skeletal muscle

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100%

Figure 8.Mn⁺² quenching of Fura-2 in FDB muscles of young muscle validates the use of BEL as an effective SOCE blocker.Enzymatically dissociated FDB muscle fibers were tested for their SOCE activity using the Mn⁺² quenching assay. BEL was able to block most 90% of the SOCE response under these experimental conditions.