Figure 3.Doxorubicin modulates the expression of cardiac hypertrophy-associated genes in H9c2 myocytes. QT-PCR analysis of MLC-2v, α-MHC and ANP transcripts in cells treated with the indicated concentrations of doxorubicin for 2 hours followed by a 24 hour treatment in fresh media. Fold change of mRNA expression shown relative to untreated control H9c2 cells; mean ± standard deviations of triplicates from a representative experiment (total of three independent experiments) are indicated.
