Research Paper Volume 2, Issue 10 pp 650—658

Figure 3. Impaired telomerase activity reduces number and size of insulin-containing pancreatic islets. (A) Depicts a typical control islet, while (B) reflects a typical islet from an Terc-/- G4 animal; red bars are 20 μm of length. (C, D) depict insulin-positive area size normalized to whole pancreatic section area only (C) and additionally normalized to body mass (D). (E, F) shows the number of islets per pancreatic section (E) and after additional normalization to body mass (F). (G, H) depict the sizes of individual insulin-positive areas per se (G) and after normalization to body mass (H). Black bars reflect control genotypes (n=25) and grey bars indicate Terc-/- G4 animals (n=10).