Hypothesis Volume 2, Issue 5 pp 265—273
Why men age faster but reproduce longer than women: mTOR and evolutionary perspectives
Figure 4. Program of puberty and quasi-program of menopause. The TOR pathway in the hypothalamus and the ovary is activated by growth factors, hormones (leptin, estrogens and FSH, LH, respectively) and nutrients. This activation starts menarche and then leads to menopause.