Figure 5.Long-lived takeout overexpressing flies have increased expression of a subset of the upregulated genes found in DR, dSir2 overexpression and DN-Dmp53 expressing flies.Overexpression of takeout in
adult neurons increases the expression of a subset of 9 genes from the 19
upregulated genes shared in yw/w1118 DR, dSir2
overexpression and DN-Dmp53 expressing long-lived flies at Day 10. Fold
change increase by qPCR of each of the noted genes using mRNA extracted
from 10-Day old flies induced to express takeout
(Elav-GeneSwitch-UAS-to) as compared to genetically identical controls
Elav-GeneSwitch; UAS-to flies without fed diluent.
