Research Perspective Volume 2, Issue 4 pp 231—237
Living on the edge: stress and activation of stress responses promote lifespan extension
Figure 1. Activation of Sty1 stress response pathway is required for life extension upon calorie restriction. Scheme depicting the role of the Sty1 pathway on life-span promotion (see text for details). Strains 972 (WT), AV18 (Δsty1) and AV15 (Δatf1) were grown in YE-1% glucose media (calorie restriction condition) and YE-4% glucose media (glucose-rich conditions). At the logarithmic phase (Log) or 120 hours after reaching the stationary phase (Day 5) serial dilutions of the cultures were plated onto YE plates.