Figure 1.Activation of Sty1 stress response pathway is required for life extension upon calorie restriction. Scheme depicting the role of
the Sty1 pathway on life-span promotion (see text for details).
Strains 972 (WT), AV18 (Δsty1) and AV15 (Δatf1) were grown in YE-1%
glucose media (calorie restriction condition) and YE-4% glucose media
(glucose-rich conditions). At the logarithmic phase (Log) or 120 hours
after reaching the stationary phase (Day 5) serial dilutions of the
cultures were plated onto YE plates.
