Figure 6.A schematic model describing the effect of feeding regimens on longevity through peripheral and SCN clock resetting. CR and IF reset
circadian rhythms in the periphery and the SCN. The synchronized, robust
circadian rhythms could be the mediator though which these feeding regimens
lead to aging attenuation and life span extension. RF resets circadian
rhythms only in the periphery, but its effect on life span is not known.