Figure 3 — Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1

Priority Research Paper|Volume 1, Issue 12|pp. 979–987

Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1

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Figure 3.Continuous administration of NAC increases lifespan of Bmal1-/- mice. Kaplan-Meyer survival curves were obtained for WT mice raised on regular (closed circles) or NAC-supplemented (open circles) water; and Bmal1-/- mice raised on regular (closed triangles) or NAC-supplemented (open triangles) water. NAC significantly increased lifespan of Bmal1-/- mice (P =0.022, log-rank Mantel-Haenszel test).