Research Paper Volume 1, Issue 9 pp 818—830

Figure 3. Subsarcolemmal (SS) and intermyofibrillar (IMF) mitochondrial protein import machinery components are increased in young, but not old animals in response to chronic contractile activity. (A). Representative Western blots of mtHSP70, Tim17, and Tim23 proteins in SS and IMF (B) mitochondrial subfractions isolated from the control (C) and chronically stimulated (S) limbs of young and old animals. (C) Graphical summary of the data in panels A and B expressed as the fold difference of the stimulated, over the control legs (n = 7-9). (D) Pooled results of the protein expression data in young, compared to old animals shown above in panel C, and panel B of Figure 3 (n = 74-86). Data represent the mean ± SEM. * P < 0.05, stimulated vs. control, † P < 0.05 vs. Young.