Review Volume 1, Issue 7 pp 586—597

Figure 1. Signaling pathways linking mTORC1 and mTORC2 to ageing via protein synthesis and autophagy. It should be noted that many links have been made in C. elegans and D. melanogaster and the reader is referred to Table 1 for homologs of the mammalian proteins in this figure. Inset: components of mTORC1 and mTORC2.