Figure 8B.Old and young cells of the same strains as
in A were isolated by elutriation centrifugation and
ERCs were analyzed by gel electrophoresis and Southern blotting
with an rDNA-specific probe as described in [19]. Thick arrow:
chromosomal rDNA repeats; Thin arrow: ERCs (minicircles).
Taken together, the results presented in this figure indicate
that longevity in the afo1Δ strain is not influenced by the
fob1-deletion or the presence of ERCs.
Figure 8B — The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1 | Aging
