The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1
Figure 1. Lifespans of isogenic strains afo1Δ, wild type BY4741 and BY4741 ρ0. Lifespans were determined as described previously [2] by micromanipulating daughter cells and counting generations of at least 45 yeast mother cells on synthetic complete (SC) media with 2% glucose as carbon source.