Research Paper Volume 1, Issue 4 pp 382—388

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

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Figure 2. In another AD case, age 63, adjacent hippocampal tissue sections demonstrate many of the AD-related pathological structures (arrows) containing pMcm2 (A) are also positive for hyper-phosphorylated tau (B) in the CA1 region. Lower magnification of adjacent sections of the subiculum shows the large number of NFT and plaques recognized by pMcm2 (C) and AT8 (D). * denotes landmark vessel. Scale bars= 50 μm (A,B), 100 μm (C,D).