Figure 2.Re-interpretation of the hyperlipidemic side effect of rapamycin. Rapamycin
activates adipose tissue lipase, thus mobilizing lipids from the fat tissue
(lipolysis). This effect imitates starvation. Also, rapamycin inhibits
lipoprotein lipase thus preventing utilization of lipids by the fat tissue
and blocking lipid uptake by the arterial wall. This results in increase
in blood lipids.
