Research Paper Volume 1, Issue 2 pp 234—244
Cyclooxygenase-1 null mice show reduced neuroinflammation in response to β-amyloid
Figure 5. Effects of COX-1 deficiency on PG production 24 h after Aβ 1-42 administration. Aβ1-42-injected WT mice show significantly more PGE2 (A), PGF2α (B), and TXB2 levels (C) than COX-1-/- mice. Mean ± SEM (n = 3-4 per group); *P < 0.05, **P < 0.01 compared with the Aβ42-1-injected WT mice; #P < 0.05, ##P < 0.01 compared with the Aβ1-42-injected WT mice.