Research Paper Volume 1, Issue 2 pp 234—244

Figure 3. Increased degenerating neurons in the hippocampus 7 d after. Aβ_1-42 administration. (A-C) Representative photomicrographs of the CA3 of the hippocampus from WT mice (A) injected with Aβ_1-42 that shows numerous FJB-positive cells compared with Aβ_1-42-injected COX-1^-/- mice (B). Representative photomicro-graphs of DAPI (D-F) and Nissl staining (G-I) in the CA3 of hippocampus from Aβ_1-42-injected WT (D, G) and COX-1^-/-mice (E, H). Scale bar: A-I, 100 μm. (J) Comparison of the number of FJB-positive cells from the CA3 area. Mean ± SEM (n = 3-4 per group); ^**P < 0.01 compared with the Aβ_42-1-injected WT mice; ^##P < 0.01 compared with the Aβ_1-42-injected WT mice.