Figure 2. Increased astrocytic activation in the hippocampus 7 d after Aβ 1-42 administration. Representative photomicrographs of the CA1 and CA3 of the hippocampus from WT mice (A, D, G) injected with Aβ1-42 that shows numerous robustly GFAP-immunoreactive astrocytes compared with Aβ1-42-injected COX-1-/- mice (B, E, H). Scale bar: A-F, 100 μm; G-I, 50 μm.