Research Paper Advance Articles

Figure 2. Distribution of methylation states of young and old samples at loci highly correlated between entropy and age. Each column of the grid below the histograms corresponds to a distinct methylation pattern, where black corresponds to an unmethylated CpG site and white corresponds to a methylated one. (A, B) Methylation pattern distributions at chr15:51681883-51681783, where average methylation and methylation entropy were positively correlated with age. (C, D) Methylation pattern distribution at chr2:101001739-101001859, where average methylation and methylation entropy were positively and negatively correlated with age, respectively.