Research Paper Volume 17, Issue 2 pp 588—606

Pan-cancer analysis of Methyltransferase-like 16 (METTL16) and validated in colorectal cancer

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Figure 8. Construction and correlation analysis of the ceRNA network. (A) Venn graph showing the prediction results of METTL16 targets in Starbase, miRDB and TargetScan tools. (B) The triple regulatory network of ceRNA. The ellipses denote mRNA, rectangles denote miRNA and diamonds denote lncRNAs. (C) ten hub genes in this network. (D) The cellular localization for six hub-lncRNAs (XIST, SNHG14, NEAT1, LINC00943, KCNQ1OT1, DHRS4-AS1) was predicted using lncLocator. (E) The Sankey diagram of the lncRNA-miRNA-mRNA (METTL16) network in line with the ceRNA hypothesis.