Research Paper Volume 17, Issue 2 pp 588—606

Pan-cancer analysis of Methyltransferase-like 16 (METTL16) and validated in colorectal cancer

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Figure 7. Effect of METTL16 in CRC cell proliferation and migration. (A) transcription level of METTL16 in CRC cell lines and NCM460. (B) transcription level of METTL16 in SW620 and SW480 were significantly downregulated by si-METTL16 transfection, respectively. (C, D) cell proliferation was assessed by CCK-8 and colony assays. (E) transwell assay employed to detect the migration ability of METTL16 knockdown cells. *p < 0.05; **p < 0.01; ***p < 0.001.