Research Paper Advance Articles
Transcriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP)
Figure 5. Gene expression is altered in PRP-treated patients with sustained implantation (Group 2) compared to control patients without sustained implantation (Group 3). (A) The heat map illustration shows differentially expressed genes. The color spectrum ranging from red to blue indicates normalized levels of gene expression from high to low. (B) Volcano plots for RNA-seq comparing PRP-LB with C-NP. (C) Differentially expressed genes in Group 2 versus Group 3, P < 0.05 for each. For the box plots, the bottom and top whiskers denote 5 and 95 percentile values, the bottom and top bounds of the rectangle denote the 25 and 75 percentile values, and the line in between denotes the median (50 percentile) value of the distribution. (D) PCA plots for RNA-seq for significant genes comparing Group 2 with Group 3. The transcripts per million (TPM) value represents the relative expression level comparable between samples.