Research Paper Volume 17, Issue 2 pp 365—392

Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis

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Figure 10. NLRP3 inflammasome analysis in control (C1, C2) and MS (P1, P2) fibroblasts. (A) Immunoblotting analysis of proteins related to NLRP3 inflammasome. Actin was used as the loading control. (B) Band densitometry of Western Blot data normalized to the mean of controls and referred to actin levels. Data represent the mean ± SD of three separate experiments. ***p-value < 0.0001 between control and MS cells.