Research Paper Volume 17, Issue 2 pp 357—364

Figure 1. Long Rep1 allele carriers showed significant decline in non-motor functions. Specifically significant findings were noted in (A) global cognitive function, measured by MoCA, (B) apathy, measured by Apathy scale and (C) attention and memory, measured by NMSS Domain 5. Results are generated using linear mixed model analysis, controlling for potential confounders including age, gender, disease duration, APOE4 status, baseline H&Y status (and baseline MoCA score for evaluation of apathy and attention and memory).